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Image Search Results
Journal: Molecular medicine reports
Article Title: microRNAs mediate oleic acid-induced acute lung injury in rats using an alternative injury mechanism.
doi: 10.3892/mmr.2014.2155
Figure Lengend Snippet: Figure 4. IHC with monoclonal anti-α-actin antibody was performed 6 and 24 h after OA-induced ALI. The figures are representative microphotographs from each category. (A) IHC of a control group sample at 6 h. Positivity for α-SMA is observed in tangentially sectioned basal epithelial cells and along the BM of bronchial epithelium; (B) IHC of the control group 24 h after OA-induced ALI. Fluorescent activity in the alveolar wall was similar to the IHC result at 6 h; (C) IHC of the OA group sample 6 h after OA-induced ALI. Alveolar wall edema and mucus secretion in the alveolar space were observed (asterisk). DAB staining in the epithelial cells (arrowhead) and in a wide area of stromal connective tissue underneath the BM was observed. (D) Increased DAB staining in the alveolar BM (arrowhead), smooth muscle of the bronchial wall or of the blood vessels (arrows) was revealed 24 h after OA-induced ALI. Thick mucus secretion was found in the alveolar spaces (asterisk) 24 h after OA-induced ALI. IHC, immunohistochemical staining; OA, oleic acid; ALI, acute lung injury; BM, basement membrane; DAB, diaminobenzidine.
Article Snippet: The measurement of the concentration of IL-13 in bronchoalveolar lavage (BAL) supernatant was performed by ELISA with
Techniques: Control, Activity Assay, Staining, Immunohistochemical staining, Membrane
Journal: Melanoma Research
Article Title: Potential clinical and immunotherapeutic utility of talimogene laherparepvec for patients with melanoma after disease progression on immune checkpoint inhibitors and BRAF inhibitors
doi: 10.1097/CMR.0000000000000444
Figure Lengend Snippet: CD4 + and CD8 + T cell infiltration of in-transit melanoma metastasis after 1 year of intralesional administration of talimogene laherparepvec. A solitary in-transit melanoma metastasis was biopsied and analyzed by IHC for the presence of HMB45 + melanoma cells, CD4 + T cells, and CD8 + T cells. Infiltration of CD4 + T cells and CD8 + T cells was noted in the peripheral aspects of the mass, which was largely devoid of melanoma cells determined by HMB45 staining.
Article Snippet: Antibodies (Cell Marque Corporation, Rocklin, California, USA) used included mouse anti-HMB45 antibody (clone HMB-45, 282M-96; Cell Marque Corporation),
Techniques: Staining